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HubLE Archive

Investigating and analysing the effects of extracellular pH on osteoclast biology

9 December 20251 July 2021 by Bethan Kate Davies
Categories HubLE Archive Tags Automated analysis, basic research, bone resorption, ECTS, ECTS 2021, Extracellular pH, Fusion, Machine learning, Osteoclasts

Osteoporosis in mastocytosis

9 December 20251 July 2021 by Christof Wilke
Categories HubLE Archive Tags Cutaneous mastocytosis, ECTS, ECTS 2021, Osteoporosis, Retrospective analysis, Retrospective study, Systemic mastocytosis Leave a comment

MicroRNAs as biomarkers for diabetic bone disease

9 December 202510 June 2021 by Ankita Duseja
Categories HubLE Archive Tags cortical bone; trabecular bone; biomarker, ECTS, ECTS 2021, MicroRNA; epigenetics; diabetes; fracture risk; bone remodeling, Translational

Characterization of osteoclast diversity to unravel functional differences and to identify selective targeting options

9 December 20259 June 2021 by Julia Halper
Categories HubLE Archive Tags Basic, ECTS, ECTS 2021, osteoclast, Osteoclastogenesis, osteoprogenitors

Generating Craniosynostosis disease models with Prime-editing

9 December 20258 June 2021 by Max Gijsbertsen
Categories HubLE Archive Tags Basic, Craniosynostosis, DNA, ECTS, ECTS 2021, genome, mutation, Prime-editing Leave a comment

Metabolic regulation of chondrocyte function during bone development

9 December 20257 June 2021 by Steve Stegen
Categories HubLE Archive Tags amino acid, Basic, cartilage, chondrocyte, chondrocyte proliferation, ECTS, ECTS 2021, glutamine, Metabolic regulation, serine Leave a comment

Tissue-level mechanical stimuli drive bone formation and resorption in humans and mice

9 December 20254 June 2021 by Matthias Walle
Categories HubLE Archive Tags Basic, bone formation, Bone mechanoregulation, bone remodeling, bone resorption, diabetes, ECTS, ECTS 2021, loading, Longitudinal high-resolution computed tomography, mechanical signal, Translational Leave a comment

CRISPR/Cas9 mediated fluorescent reporter mice for osteoblasts and osteoclasts to study bone mechanomics

9 December 20253 June 2021 by Dilara Yilmaz
Categories HubLE Archive Tags Age-related osteoporosis, Basic, bone adaptation, CRISPR/Cas9, ECTS, ECTS 2021, fluorescent, osteoblast, osteoclast, Reporter mice model

We should put more efforts to support and engage with trainees from emerging and developing countries

9 December 20255 May 2021 by Diego Grinman
Categories HubLE Archive Tags developing countries, diversity, emerging countries, inclusion Leave a comment

To use in silico modeling, and specifically an agent-based multiphysics model, to assist in the design of clinical trials, and test hypotheses as to bone mechanobiology

9 December 20255 May 2021 by Charles Ledoux
Categories HubLE Archive Tags bisphosphonate, clinical trial, denosumab, in silico modelling, mechanobiology, menopause, translational research
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